ملخص: This thesis is divided into two parts : The first part describes an enantiospecific synthesis of the diastreoisomeric asperlin which establishes the absolute configuration of the natural asperlin, using carbohydrates as chiral precursors. The strategy for this synthesis involves tandom epoxide/Wadsworth-Emmons-Horner olefination. The second part is concerned with the study of asymmetric Diels-Alder reactions using acrylates containing chiral auxiliaries derived from L -(+)- arabinose. A series of chiral auxiliaries with different aromatic aglycones have been prepared from arabinose involving acetobromination, Koenigs-acryloylation. Work on the preparation od C-glycosylated sugar as chiral auxiliaries have also been investigated.

طبعة: Manchester: University of Manchester
لغة: إنجليزية
الوصف المادي: 112 p. ill. ;30 cm
الشهادة: Master
مؤسسة مناقشة الرسالة: Departement of Chemistry

ملاحظة: Bibliogr.pp.108-112